乙酰化降低了肽对细菌的活性。Cr-ACP1(苏铁抗癌肽1,植物)具有抗癌、抗菌活性。Cr-ACP1(苏铁抗癌肽 1,植物)在苏铁种子中被发现。
Acetylation reduced peptide activity against bacteria. Cr-ACP1 (C. revoluta anticancer peptide 1, plants) has Anticancer, Antibacterial activity. Cr-ACP1 (C. revoluta anticancer peptide 1, plants) was found in seeds, Cycas revoluta.
单字母 H2N-AWKLFDDGV-OH
多字母 H2N-Ala-Trp-Lys-Leu-Phe-Asp-Asp-Gly-Val-OH
氨基酸个数 9
分子式 C50H71N11O14
平均分子量(MW) 1050.16
精确分子量(Exact Mass)(MW) 1049.52
等电点(PI) 6.4
pH=7.0时的净电荷数 -0.02
GRAVY 0.04
亲水残基比例 0.18
消光系数 5500
溶解建议 疏水
参考文献:
Mandal SM, Migliolo L, Das S, Mandal M, Franco OL, Hazra TK. Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. J Cell Biochem. 2012;113(1):184-93.