Lariains B 由 20 个 L 型氨基酸残基组成，其内部存在谷氨酸 8 位的γ-羧基与甘氨酸 1 位的α-氨基之间的连接。Lariains A 和 B 在琼脂稀释法中对鸟分枝杆菌的生长抑制作用的最小抑菌浓度（MIC）值分别为 3.13 毫克/毫升和 6.25 毫克/毫升。此外，Lariatin A 在液体微量稀释法中对结核分枝杆菌的生长抑制作用的 MIC 值为 0.39 毫克/毫升。

Lariains B consists of 20 L-amino acid residues with an internal linkage between the γ-carboxyl group of Glu8 and the alpha-amino group of Gly1. Lariains A and B showed growth inhibition against Mycobacterium smegmatis with MIC values of 3.13 and 6.25 mg/ml in agar dilution method, respectively. Furthermore, lariatin A inhibited the growth of Mycobacterium tuberculosis with an MIC of 0.39 mg/ml in liquid microdilution method.

单字母 H2N-GSQLVYREWVGHSNVIKGPP-OH (γ-carboxyl group of Glu8 and the alpha-amino group of Gly1 forms a ring)
多字母 H2N-Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Gly-Pro-Pro-OH (γ-carboxyl group of Glu8 and the alpha-amino group of Gly1 forms a ring)
氨基酸个数 20
分子式 C101H155N29O28
平均分子量(MW) 2223.49
精确分子量(Exact Mass)(MW) 2222.16
等电点(PI) 11.71
pH=7.0时的净电荷数 3.21
GRAVY -0.45
亲水残基比例 -
消光系数 6990
溶解建议 疏水

参考文献：
Iwatsuki M, Tomoda H, Uchida R, Gouda H, Hirono S, Omura S. Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure. J Am Chem Soc. 2006;128(23):7486-91.